Predictors of Pre-Term Births Among Women Delivering at Migori County Referral Hospital, Migori, Kenya

  • Martin Eyinda Jomo Kenyatta University of Agriculture and Technology
  • Jackline Mosinya Nyaberi, PhD Jomo Kenyatta University of Agriculture and Technology
  • Charles Nyamori Orora Jomo Kenyatta University of Agriculture and Technology
Keywords: Preterm, Predictors, Prevalence, Birth
Share Article:

Abstract

Introduction: Preterm birth is defined as babies born before 37 completed weeks of pregnancy or fewer than 259 days since the first day of a woman’s last menstrual period. Globally, approximately 15 million children are born pre-term, and the WHO has estimated a global pre-term prevalence of between 4-16%. In 2020 it is estimated that more than one million neonates died due to complications of preterm birth and millions more survived with lifelong disabilities. Sub-Saharan Africa (SSA) and Southern Asia account for 60% of pre-term birth prevalence, and most of these countries lack reliable data on the burden and predictors of pre-term birth. This study investigated the prevalence and predictors of pre-term birth at Migori County Referral Hospital (MCRH) in Kenya. Method: This was a cross-sectional study conducted in MCRH where a systematic sampling method was used to enrol 692 mothers who delivered at the hospital between April and June 2023. Hospital records were reviewed, and an online semi-structured questionnaire was used to collect maternal, fetal and institutional characteristics. The prevalence of preterm births was calculated, and binary logistic regression was performed to identify the predictors of preterm births. 95% CI and P-values <0.05 were used to identify significant predictors of preterm birth. Results: The prevalence of preterm births was found to be 15.4%. Previous history of preterm births (AOR 2.5, 1.2-5.4), and syphilis in pregnancy (AOR 6.3, 1.5-2.7) were significant predictors of preterm births. Attending ANC was found to be a protective factor against preterm births by 87% (AOR = 0.13 (0.02– 0.71), p = 0.018). Conclusion: The prevalence of preterm births at MCRH was high, underscoring the significance of addressing this issue within the community.  History of preterm births and syphilis were predictors of preterm births. ANC attendance was identified as a protective factor against preterm birth

Downloads

Download data is not yet available.

References

WHO. New global estimates on preterm birth published [Internet]. 2018 [cited 2023 Nov 14]. Available from: https://www.who.int/news/item/17-11-2018-new-global-estimates-on-preterm-birth-published

Maternal, Newborn, Child & Adolescent Health & Ageing (MCA). (2023, May 9). Born too soon: a decade of action on preterm birth. https://www.who.int/publications/i/item/9789240073890

Chawanpaiboon, S., Vogel, J. P., Moller, A. B., Lumbiganon, P., Petzold, M., Hogan, D., ... & Gülmezoglu, A. M. (2019). Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis. The Lancet Global Health, 7(1), e37-e46.

Bekele, I., Demeke, T., & Dugna, K. (2017). Prevalence of preterm birth and its associated factors among mothers delivered in Jimma university specialized teaching and referral hospital, Jimma Zone, Oromia Regional State, Southwest Ethiopia. J Women’s Health Care, 6(1), 1-10.

Lee AC, Katz J, Blencowe H, Cousens S, Kozuki N, Vogel JP, et al. National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010. Lancet Glob Health. 2013;1(1):e26–36

Ayele, T. B., & Moyehodie, Y. A. (2023). Prevalence of preterm birth and associated factors among mothers who gave birth in public hospitals of east Gojjam zone, Ethiopia. BMC pregnancy and childbirth, 23(1), 204.

Ashtekar SD, Kumbhar SK, Ashtekar RS. Study of premature babies in relation to their outcome and Antenatal risk factors at general hospital Sangli. J Evol Med Dent Sci. 2014;3(30):8506–11.

Wagura P, Wasunna A, Laving A, Wamalwa D, Ng’ang’a P. Prevalence and factors associated with preterm birth at Kenyatta National Hospital. BMC Pregnancy Childbirth. 2018;18(1):1–8.

Lawn JE, et al. Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data. BMC

Onankpa B, Isezuo K. Pattern of preterm delivery and their outcome in a tertiary hospital. Int J Health Sci Res. 2014;4(3):59–65

van den Broek NR, Jean-Baptiste R, Neilson JP. Factors associated with preterm, early preterm and late preterm birth in Malawi. PLoS ONE.2014;9(3):e90128

Imbo, A. E., Mbuthia, E. K., & Ngotho, D. N. (2021). Determinants of Neonatal Mortality in Kenya: Evidence from the Kenya Demographic and Health Survey 2014. International Journal of MCH and AIDS, 10(2), 287–295. https://doi.org/10.21106/ijma.508

Waitzman NJ, Jalali A, Grosse SD. Preterm birth lifetime costs in the United States in 2016: an update. In seminars in Perinatology. Elsevier; 2021.

Woldeyohannes D, et al. Factors associated with preterm birth among mothers who gave birth in Dodola town hospitals, Southeast Ethiopia: institutional based cross-sectional study. Clin Mother Child Health. 2019;16(317):2.

Adugna DG. Prevalence and associated risk factors of preterm birth among neonates in referral hospitals of Amhara Region, Ethiopia. PLoS ONE.2022;17(10):e0276793.

Gebreslasie K. Preterm birth and associated factors among mothers who gave birth in Gondar town health institutions Advances in Nursing, 2016. 2016 Pregnancy Childbirth. 2010;10(1):1–22.

Wang, X., & Cheng, Z. (2020). Cross-Sectional Studies: Strengths, Weaknesses, and Recommendations. Chest, 158(1S), S65–S71. https://doi.org/10.1016/j.chest.2020.03.012

Ohuma, E. O., Moller, A. B., Bradley, E., Chakwera, S., Hussain-Alkhateeb, L., Lewin, A., ... & Moran, A. C. (2023). National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis. The Lancet, 402(10409), 1261-1271.

Kenya National Bureau of Statistics, Ministry of Health/Kenya, National AIDS Control Council/Kenya, Kenya Medical Research Institute, & National Council for Population and Development/Kenya. (2015, December 1). Kenya Demographic and Health Survey 2014. https://dhsprogram.com/publications/publication-FR308-DHS-Final-Reports.cfm.

Okube, O. T., & Sambu, L. M. (2017). Determinants of preterm birth at the postnatal ward of Kenyatta National Hospital, Nairobi, Kenya. Open Journal of Obstetrics and Gynecology, 7(9), 973-988.

Story, L., Simpson, N. A., David, A. L., Alfirevic, Z., Bennett, P. R., Jolly, M., & Shennan, A. H. (2019). Reducing the impact of preterm birth: preterm birth commissioning in the United Kingdom. European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 3, 100018.

Wakeyo, D., Addisu, Y., & Mareg, M. (2020). Determinants of Preterm Birth among Mothers Who Gave Birth in Dilla University Referral Hospital, Southern Ethiopia: A Case‐Control Study. BioMed research international, 2020(1), 7031093.

Shubhada S. A., Kambale S. V., and Phalke B. D., Determinants of preterm labour in a rural medical college hospital in western Maharashtra, Nepal Journal of Obstetrics and Gynaecology. (2013) 8, no. 1, 31–33.

Rai R. K., Sudfeld C. R., Barik A., Fawzi W. W., and Chowdhury A., Sociodemographic determinants of preterm birth and small for gestational age in rural West Bengal, India, Journal of Tropical Pediatrics. (2019) 65, 537–546s

Belaynew W., Teumay A., Getachew G., and Mohamed K., Effects of inter-pregnancy interval on preterm birth and associated factors among postpartum mothers who gave birth at Felege Hiwot referral hospital, World Journal of Pharmaceutical Sciences. (2015) 4, no. 4, 12–25

Koullali, B., Van Zijl, M. D., Kazemier, B. M., Oudijk, M. A., Mol, B. W., Pajkrt, E., & Ravelli, A. C. (2020). The association between parity and spontaneous preterm birth: a population-based study. BMC pregnancy and childbirth, 20, 1-8.

Bai J, Wong FWS, Bauman A, Mohsin M. Parity and pregnancy outcomes. Am J Obstet Gynecol. 2002;186(2):274–8

Jacquemyn Y, Senten L, Vellinga S, Vermeulen K, Martens G. Does practice make perfect? An age-matched study on grand multiparity in Flanders. Belgium J Perinat Med. 2006;34(1):28–31

Baer RJ, Chambers CD, Ryckman KK, Oltman SP, Rand L, Jelliffe-Pawlowski LL. An evaluation of sexually transmitted infection and odds of preterm or early-term birth using propensity score matching. Sex Transm Dis. 2019;46(6):389-394. doi:10.1097/OLQ.0000000000000985

Mann JR, McDermott S, Gill T. Sexually transmitted infection is associated with increased risk of preterm birth in South Carolina women insured by Medicaid. J Matern Fetal Neonatal Med. 2010;23(6):563-568. doi:10.3109/14767050903214574

Johnson HL, Ghanem KG, Zenilman JM, Erbelding EJ. Sexually transmitted infections and adverse pregnancy outcomes among women attending inner-city public sexually transmitted diseases clinics. Sex Transm Dis. 2011;38(3):167-171. doi:10.1097/OLQ.0b013e3181f2e85f

Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371(9606):75-84. doi:10.1016/S0140-6736(08)60074-4

Bogavac M, Brkić S, Simin N, Grujić Z, Bozin B. Do bacterial vaginosis and chlamydial infection affect serum cytokine level? Srp Arh Celok Lek. 2010;138(7-8):444-448. doi:10.2298/SARH1008444B

- Pervin, J., Rahman, S. M., Rahman, M., Aktar, S., & Rahman, A. (2020). Association between antenatal care visit and preterm birth: a cohort study in rural Bangladesh. BMJ open, 10(7), e036699.

- Organization WH. WHO recommendations on antenatal care for a positive pregnancy experience: World Health Organization; 2016.

Mochama RS, Esamai F, Rotich E. Outcomes for preterm babies during the neonatal period in Kisii teaching and referral hospital, Kenya. Glob J Health Sci. 2019;4(1):1–10.

Etuk SJ, Etuk IS, Oyo-Ita AE. Factors influencing the incidence of pre-term birth in Calabar, Nigeria. Niger J Physiol Sci. 2005;20(1):63–8.

Sebayang SK, Dibley MJ, Kelly PJ, Shankar AV, Shankar AH, Group SS. Determinants of low birthweight, small‐for‐gestational‐age and preterm birth in Lombok, Indonesia: analyses of the birthweight cohort of the SUMMIT trial. Trop Med Int Health. 2012;17(8):938–50.

Feresu SA, Harlow SD, Welch K, Gillespie BW. Incidence of and socio‐demographic risk factors for stillbirth, preterm birth and low birthweight among Zimbabwean women. Paediatr Perinat Epidemiol. 2004;18(2):154–63.

Mokuolu OA, Suleiman BM, Adesiyun OO, Adeniyi A. Prevalence and determinants of pre-term deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria. Pediatr Rep. 2010;2(1):e3.

Khalajinia Z, Jandaghi G. Maternal risk factors associated with preterm delivery in Qom province of Iran in 2008. Sci Res Essays. 2012;7(1):51–4.

Shahira R D, Hanan M ET, Nagla M A, Moustafa A E, Mohamed E. Urinary tract infection and adverse outcome of pregnancy. 2007.

Pusdekar YV, Patel AB, Kurhe KG, Bhargav SR, Thorsten V, Garces A, et al. Rates and risk factors for preterm birth and low birthweight in the global network sites in six low- and low middle-income countries. Reprod Health. 2020 Dec 17;17(3):187.

Naiknaware S. Antepartum Haemorrhage: Causes & Its Effects on Mother and Child: An Evaluation. Obstet Gynecol Int J. 2015 Nov 4;3.

Published
24 October, 2024
How to Cite
Eyinda, M., Nyaberi, J., & Orora, C. (2024). Predictors of Pre-Term Births Among Women Delivering at Migori County Referral Hospital, Migori, Kenya. East African Journal of Health and Science, 7(2), 1-14. https://doi.org/10.37284/eajhs.7.2.2333